Tag Archives: depression

In Brief: Postpartum Depression Common in COVID-Positive Women Separated from Their Newborns

In Brief: Postpartum Depression Common in COVID-Positive Women Separated from Their Newborns Soon after the COVID-19 pandemic emerged, the American Academy of Pediatrics recommended temporarily separating newborns from mothers who tested positive for COVID-19 immediately after delivery. In a retrospective cohort study of 224 new mothers delivering at a New York hospital between March 18… Read More »

More Data on the Neuroactive Steroid Zuranolone for Postpartum Depression

While we have heard a lot about brexanolone, marketed by Sage Therapeutics as Zulresso, for the treatment of postpartum depression, an oral version of this novel antidepressant – SAGE 217 or zuranolone – has been finishing up its Phase 3 trials. Like brexanolone, SAGE-217 is a neuroactive steroid, an analogue of allopregnanolone which is a… Read More »

Perimenopausal Depression in Women with More Variable Levels of Estradiol and Lower Progesterone Levels

Women are at increased risk for depressive symptoms during the menopause transition.  It has long been suspected that falling estrogen levels play a role in triggering the onset of depression; however, if all women experience declining levels of estrogen and progesterone during this transition, why is it that only some women suffer from depression in… Read More »